Orion Corporation operates in more than 20 countries, where we Orionees, 3200 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.

Description of position:

We are seeking a motivated individual for a genetic toxicology scientist in the Investigative Toxicology & ADME group within Research & Development. Your primary responsibility is to act as genetic toxicology expert in all phases of drug discovery and development. You will design and implement genotoxicology testing and assessment strategies both in lead optimization to support the nomination of Orion's small molecule and biologics drug candidates as well as in drug development phase. You will also work as a safety expert in multidisciplinary early drug discovery project teams. In that position you will support projects, by collecting and interpreting complex data from various in vitro safety and toxicology profiling and screening assays, document and communicate results to aid in lead series prioritization, lead optimization and drug candidate selection. You will provide scientific oversight for regulatory non-clinical genetic toxicology studies conducted in contract research organizations (CROs). A part of your job is contributing to regulatory submissions and interactions with regulatory authorities.

The position level is dependent upon the candidate's level of experience. The location will be in Espoo or Turku, Finland.

Description of unit

Orion's pharmaceutical innovations are created within its R&D organization, including e.g. non-clinical research and clinical development. The organization employs top professionals in the field of drug development. 

Investigative Toxicology & ADME organization is part of Global Translational Pharmacology & Safety Sciences at Orion R&D. The organization is responsible for the early safety and ADME assessment of new drug candidates during various stages of the drug discovery and development process.

We offer

We offer exciting opportunities to create and have an impact to the future therapies for patients. 

In Orion we have a highly interesting R&D pipeline and enthusiastic working environment with opportunities to use your own strengths to build your competence development and career. As an expert of your own field you will be a member of multi-disciplinary team jointly innovating and developing new treatments for the patients. Appreciation of colleagues and continuous development are part of our core values. The culture of Orion R&D is informal and we enjoy working together. 

We are passionate about the patient welfare and our R&D vision is Translating world-class science into novel life-changing therapies - if this inspires you too - join us!

Requirements

You are expected to have:

• MSc/PhD in toxicology, biochemistry, pharmacology or related sciences with preferably at least 5 years of experience in the field of genetic toxicology or non-clinical safety with deep understanding of mechanisms of genotoxicity
• Experience in pharmaceutical industry would be a plus
• A keen understanding of experimental design, underlying scientific principles and the ability to rigorously analyze and interpret complex data, and further, effectively document and communicate results
• Demonstrated good team and networking skills
• Excellent presentation and communication skills in English
• Enthusiastic, innovative and science-oriented mindset

We also appreciate:

• Working knowledge of various international regulatory guidances relevant to genotoxicology and drug development
• Experience or knowledge in computational toxicology and structure-activity-relationship relevant to mutagenicity

Contact information

If you see yourself as an excellent and energetic team player check out our website and apply for this position with your salary request by February, 5th at the latest!

For more information contact Teija Oinonen (+358 509663730) during January 23th at 12.30-13.30 or 30th at 9.30-10.30 or February 3th klo 15-16.

Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person.