Description of Position

Antibody-Drug Conjugates Research Team is seeking a highly motivated, skilful, and independent Senior Scientist with experience in preclinical cancer research. You should have a track record of scientific excellence in modern cell- and molecular biology-based methodologies. As Senior Scientist you will work collaboratively with a multidisciplinary team of scientists and researchers to advance the discovery of novel cancer targets and participate in the development of the first/best-in-class Antibody-Drug Conjugates (ADCs) from concept to clinical candidate phase. This position offers an exciting opportunity to apply the candidate's expertise in cancer research and contribute to the development of potentially lifesaving therapies.

Key Responsibilities

The candidate for this position will:

• Develop and execute strategies for target identification and evaluation.
• Perform target validation studies such as analysis of target expression, quantification, distribution, internalization, and intracellular trafficking.
• Conduct and/or coordinate in vitro experiments to assess the critical properties of ADCs and their components.
• Establish and implement novel assays to characterize ADCs.
• Provide cancer biology expertise and guidance for the project team/organization.
• Collaborate with cross-functional teams, including medicinal chemists, pharmacologists, biologists, and clinical researchers to answer scientific questions and drive projects forward.
• Take charge of collaborations and externally partnered research.
• Perform data analysis of experimental results and regularly report work progress in the project team and organization meetings.

This permanent position is based in Turku, Finland, and you will report to the Head of the Antibody-Drug Conjugates Team.

Description of Unit 

Antibody-Drug Conjugates Team is one of three scientific units in Oncology Research, a part of Orion's R&D Organization. Antibody-Drug Conjugates Team is focused on the discovery of therapeutic targets and active development of ADCs utilizing a broad panel of biophysical, biochemical, cellular, and in vivo methods. Our aim is to develop cutting-edge ADC therapies that can transform cancer patients' lives.

We Offer  

At Orion we offer you, among others: 

• Opportunity to work with a dynamic and experienced team of in vitro and in vivo scientists and assistants building up Oncology Research at Orion.
• An exciting R&D pipeline and enthusiastic working environment with opportunities to use your strengths to build your competence and career.
• Exciting opportunity to innovate and have an impact on future therapies for patients.
• We have an excellent working atmosphere based on the appreciation of colleagues, continuous development, and mutual trust. Read more about our values.

In addition, Orion supports integration of international talents into Finland with the help of a relocation programme. Read more on our webpages. 

Essential Requirements

To be successful in this role, the candidate must have the demonstrated knowledge, skills, and abilities in the following: 

• Ph.D. or master's degree with 8+ years of academic or industry experience in a relevant discipline (Biological Sciences, Biochemistry or equivalent). 
• Understanding of cell and molecular biology and/or biochemistry in the context of cancer biology.
• Knowledge and hands-on experience in cell- and molecular biology-based methodologies, including multichannel/multicolour flow cytometry, fluorescent and live cell microscopy, cytotoxicity assays, fluorescent labelling, qPCR, western blotting, and ELISA.
• Experience with routine 2D cell culture models.
• Demonstrated ability to work independently and collaborate effectively as a member of a multidisciplinary research team, and mentor junior team members.
• Strong desire to continue seeking new technological innovations supporting laboratory work.
• Excellent problem-solving and critical-thinking skills.
• Strong communication and presentation skills.

Desirable Requirements 

• Experience in the design and development of biologics and/or conjugates.
• Knowledge of bioinformatics and omics-type data analysis. 
• Prior experience in the biopharmaceutical industry.

Additional Information

Applications will be accepted until the 15^th of October 2023. We will start reviewing applications during the application period.

For additional details, don't hesitate to get in touch with Dr Marcin Chrusciel, Head of Antibody Drug Conjugates Team tel. +358 509667861 on the following times (Finnish Time): 6^th of October 15:00-16:00 or 12^th of October 15:00-16:00.

#LI-ORION

Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person.


Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.